Vasorelaxant activity of indole alkaloids from Tabernaemontana dichotoma
نویسندگان
چکیده
منابع مشابه
Monogagaine, a Novel Dimeric Indole Alkaloid from Tabernaemontana chippii and Tabernaemontana dichotoma [1]
Tabernaemontana chippii and Tabernaemontana dichotoma [1] Teris A. van Beek*, Peter P. Lankhorst, Robert Verpoorte, Georges Massiot, Roel Fokkens, Cornelis Erkelens, Premila Perera, and Cecilia Tibell a Department of Pharmacognosy, Gorlaeus Laboratories, P .O.Box 9502, 2300 R A Leiden, The Netherlands b Depar tment of Organic Chemistry, Leiden, The Netherlands c Faculte de Pharmacie, Reims, Fra...
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Ten indole alkaloids from the chloroform extract of stalk of Tabernaemontana australis (Muell. Arg) Miers were tentatively identified by GC-MS, viz., coronaridine (1), voacangine (2), voacangine hydroxyindolenine (3), rupicoline (4), ibogamine (5), ibogaine (6), ibogaline (7), desethyl-voacangine (8), voachalotine (9), and affinisine (10). Of these, the first four were isolated by silica gel op...
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Leishmaniasis is a parasitic infection that is considered worldwide one of the most important public health problem, affecting more than 12 million people with an estimated number of 2 million new cases occurring annually. Among the compounds isolated from Tabernaemontana catharinensis, coronaridine and voacangine are the indole alkaloids which have antileishmanial activity. In this work, the t...
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The follow-up of phytochemical and pharmacological studies of Sida rhombifolia L. (Malvaceae) aims to strengthen the chemosystematics and pharmacology of Sida genera and support the ethnopharmacological use of this species as hypotensive herb. The present work reports phytoconstituents isolated and identified from aerial parts of S. rhombifolia by using chromatographic and spectroscopic methods...
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We evaluated the antibacterial activities of the crude methanol extract, fractions (I-V) obtained after acid-base extraction and pure compounds from the stem bark of Aspidosperma ramiflorum. The minimum inhibitory concentration (MIC) was determined by the microdilution technique in Mueller-Hinton broth. Inoculates were prepared in this medium from 24-h broth cultures of bacteria (10(7) CFU/mL)....
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ژورنال
عنوان ژورنال: Journal of Natural Medicines
سال: 2012
ISSN: 1340-3443,1861-0293
DOI: 10.1007/s11418-012-0638-y